Skeletal visualization during dynamic renal imaging is an uncommon finding that has previously been related to underlying neoplastic disease. The authors report a case of active Paget's disease of the left ilium resulting in uptake of Tc-99m DTPA in the arterial flow and early blood pool images. This report emphasizes that it is the increased blood flow, rather than the bone pathology per se, that determines uptake of Tc-99m DTPA in Paget's disease.