Psoriasis and hypertension: a case-control study

J Eur Acad Dermatol Venereol. 2012 Jun;26(6):785-8. doi: 10.1111/j.1468-3083.2011.04108.x. Epub 2011 May 14.

Abstract

Background: Several studies stated that patient with psoriasis carried an increased risk of psoriasis but some studies did not demonstrate this association.

Objectives: The aim of this study was to evaluate the prevalence of hypertension in psoriasis based on a sample of Spanish population.

Methods: This was a hospital-based case-control study involving 661 psoriatic patients (cases) and 661 control matched by gender and age. Meta-analysis of the previous studies was made.

Results: The prevalence of hypertension was significantly higher in psoriasis patients than controls (30.3%, 21.3%, respectively, P < 0.001). In a multivariate analysis, hypertension was associated with psoriasis after controlling for age, gender, diabetes, obesity and smoking (OR = 1.44, 95% confidence interval: 1.07-1.94).

Conclusion: The results of this study support the association between psoriasis and hypertension.

Publication types

  • Meta-Analysis

MeSH terms

  • Adult
  • Case-Control Studies
  • Female
  • Humans
  • Hypertension / complications*
  • Hypertension / epidemiology
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Prevalence
  • Psoriasis / complications*