Factors affecting lymph node yield from patients undergoing colectomy for cancer

Int J Colorectal Dis. 2011 Sep;26(9):1163-8. doi: 10.1007/s00384-011-1240-6. Epub 2011 May 15.

Abstract

Purpose: Lymph node (LN) yield is a critical component of colon cancer staging and is often a surrogate for quality assessment in surgery. We investigated the impact of pathologists' training on LN harvest.

Methods: This is a retrospective review on 137 patients undergoing elective colectomy for adenocarcinoma at a single institution from 2008 to 2009. We studied surgeon-, patient- and pathologist-derived factors, and identified independent variables affecting LN yield using logistic regression.

Results: LN yield was similar between open and laparoscopic resections (21 versus 23, p = 0.54). Similarly, nodal counts were independent of tumor location (p = 0.08) and no difference was noted between colorectal and general surgeons (24 versus 21, p = 0.31). Strikingly, the number of LNs reported by PGY-1 pathology residents was significantly higher than those with two or more years of training (24 versus 19, p = 0.02). On logistic regression, only the reporting pathologists' year in training remained a significant predictor of the number of nodes reported (OR = 5.28, p = 0.0001).

Conclusions: LN retrieval in patients with colon cancer is inversely related to the interpreting pathologists' level of training.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Colectomy / methods*
  • Colonic Neoplasms / pathology*
  • Colonic Neoplasms / surgery*
  • Female
  • Humans
  • Logistic Models
  • Lymph Nodes / pathology*
  • Lymph Nodes / surgery*
  • Male
  • Middle Aged