Evidence of simian virus 40 infection in multiple organ transplant recipients with renal dysfunction

Scand J Infect Dis. 2011 Sep;43(9):736-41. doi: 10.3109/00365548.2011.577803. Epub 2011 May 17.

Abstract

Electron microscopy (EM), real-time polymerase chain reaction (PCR) and conventional PCR were used to identify viruses associated with infection in 2 transplantation patients. An autologous haematopoietic stem cell, liver and renal transplant recipient was found to be positive for simian virus 40 (SV40). Dual BK virus and SV40 infection was found in a heart and renal transplantation patient. SV40 infection can occur in immunocompromised patients.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • BK Virus / isolation & purification
  • Base Sequence
  • DNA, Viral / chemistry
  • DNA, Viral / genetics
  • Female
  • Humans
  • Immunocompromised Host
  • Microscopy, Electron
  • Middle Aged
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Polyomavirus Infections / diagnosis*
  • Polyomavirus Infections / virology
  • Sequence Analysis, DNA
  • Simian virus 40 / isolation & purification*
  • Transplantation
  • Transplants / adverse effects*
  • Tumor Virus Infections / diagnosis*
  • Tumor Virus Infections / virology

Substances

  • DNA, Viral