[Papillomavirus and head and neck cancer]

G Lescaille; V Descroix; J Azérad

doi:10.1016/j.stomax.2011.03.007

[Papillomavirus and head and neck cancer]

Rev Stomatol Chir Maxillofac. 2011 Jun;112(3):160-3. doi: 10.1016/j.stomax.2011.03.007. Epub 2011 May 18.

[Article in French]

Authors

G Lescaille¹, V Descroix, J Azérad

Affiliation

¹ Service d'odontologie, UFR d'odontologie université Paris Diderot, groupe hospitalier Pitié-Salpêtrière, 43-87 boulevard de l'hôpital, Paris. France. [email protected]

PMID: 21596407
DOI: 10.1016/j.stomax.2011.03.007

Abstract

Tobacco and alcohol consumption are the main risk factors for head and neck cancers. Papillomavirus (HPV) infection was recently associated with the development of malignant tumors of the oropharynx, according to molecular and biological arguments. We describe the oncogenic mechanisms of HPV infections, the epidemiological and clinical aspects of associated head and neck cancers, their prognosis, and issues of specific therapeutic strategies.

Publication types

English Abstract

MeSH terms

Age Factors
Alcohol Drinking / adverse effects
Alphapapillomavirus / pathogenicity*
Biomarkers, Tumor / isolation & purification
Cell Transformation, Neoplastic / pathology
Female
Head and Neck Neoplasms / etiology
Head and Neck Neoplasms / virology*
Human papillomavirus 16 / pathogenicity
Humans
Male
Mouth Neoplasms / virology
Neoadjuvant Therapy
Oropharyngeal Neoplasms / virology
Papillomavirus Infections / transmission
Papillomavirus Infections / virology*
Papillomavirus Vaccines
Prognosis
Sex Factors
Smoking / adverse effects
Tongue Neoplasms / virology
Tonsillar Neoplasms / virology

Substances

Biomarkers, Tumor
Papillomavirus Vaccines