Allelic loss at markers of chromosomal band 7q31 is not a frequent event in human breast-cancer

F Kerangueven; T Noguchi; J Adelaide; J Jacquemier; H Sobol; D Birnbaum

doi:10.3892/or.2.1.89

Allelic loss at markers of chromosomal band 7q31 is not a frequent event in human breast-cancer

Oncol Rep. 1995 Jan;2(1):89-90. doi: 10.3892/or.2.1.89.

Authors

F Kerangueven¹, T Noguchi, J Adelaide, J Jacquemier, H Sobol, D Birnbaum

Affiliation

¹ INSERM,U119,27 BD LEI ROURE,F-13009 MARSEILLE,FRANCE. INST J PAOLI I CALMETTES,BIOL TUMEURS LAB,F-13009 MARSEILLE,FRANCE. INST J PAOLI I CALMETTES,DEPT ANATOMOPATHOL,F-13009 MARSEILLE,FRANCE. INST J PAOLI I CALMETTES,DEPT ONCOGENET,F-13009 MARSEILLE,FRANCE.

PMID: 21597695
DOI: 10.3892/or.2.1.89

Abstract

Loss of heterozygosity (LOH) at loci from the long arm of chromosome 7 was shown to occur in breast carcinomas. However, the frequency with which this alteration is observed varies from 0 to 40%. We report LOH at three microsatellite markers located at 7q3 in 16 of 66 (24%) breast tumor samples.