Magnetic fluid hyperthermia: focus on superparamagnetic iron oxide nanoparticles

Sophie Laurent; Silvio Dutz; Urs O Häfeli; Morteza Mahmoudi

doi:10.1016/j.cis.2011.04.003

Magnetic fluid hyperthermia: focus on superparamagnetic iron oxide nanoparticles

Adv Colloid Interface Sci. 2011 Aug 10;166(1-2):8-23. doi: 10.1016/j.cis.2011.04.003. Epub 2011 Apr 30.

Authors

Sophie Laurent¹, Silvio Dutz, Urs O Häfeli, Morteza Mahmoudi

Affiliation

¹ Department of General, Organic, and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, Avenue Maistriau, 19, B-7000 Mons, Belgium.

PMID: 21601820
DOI: 10.1016/j.cis.2011.04.003

Abstract

Due to their unique magnetic properties, excellent biocompatibility as well as multi-purpose biomedical potential (e.g., applications in cancer therapy and general drug delivery), superparamagnetic iron oxide nanoparticles (SPIONs) are attracting increasing attention in both pharmaceutical and industrial communities. The precise control of the physiochemical properties of these magnetic systems is crucial for hyperthermia applications, as the induced heat is highly dependent on these properties. In this review, the limitations and recent advances in the development of superparamagnetic iron oxide nanoparticles for hyperthermia are presented.

Publication types

Review

MeSH terms

Animals
Chemical Phenomena
Drug Delivery Systems
Humans
Hyperthermia, Induced / methods*
Magnetics
Magnetite Nanoparticles / chemistry*
Magnetite Nanoparticles / therapeutic use*
Materials Testing
Temperature

Substances

Magnetite Nanoparticles