Disrupting the reader of histone language

Angew Chem Int Ed Engl. 2011 Jun 20;50(26):5801-3. doi: 10.1002/anie.201101414. Epub 2011 May 25.
No abstract available

MeSH terms

  • Azepines / chemistry*
  • Benzodiazepines
  • Cell Cycle Proteins
  • Chromatin / chemistry
  • Chromatin / metabolism
  • Epigenesis, Genetic
  • Heterocyclic Compounds, 4 or More Rings / chemistry
  • Histone Deacetylases / chemistry
  • Histone Deacetylases / metabolism
  • Histones / chemistry*
  • Histones / metabolism
  • Humans
  • Hydroxamic Acids / chemistry
  • Nuclear Proteins / antagonists & inhibitors
  • Nuclear Proteins / genetics
  • Nuclear Proteins / metabolism
  • Protein Serine-Threonine Kinases / antagonists & inhibitors
  • Protein Serine-Threonine Kinases / genetics
  • Protein Serine-Threonine Kinases / metabolism
  • Stereoisomerism
  • Transcription Factors / antagonists & inhibitors
  • Transcription Factors / genetics
  • Transcription Factors / metabolism
  • Triazoles / chemistry*

Substances

  • (+)-JQ1 compound
  • Azepines
  • BRD2 protein, human
  • BRD4 protein, human
  • Cell Cycle Proteins
  • Chromatin
  • Heterocyclic Compounds, 4 or More Rings
  • Histones
  • Hydroxamic Acids
  • Nuclear Proteins
  • Transcription Factors
  • Triazoles
  • suberoyl bis-hydroxamic acid
  • Benzodiazepines
  • molibresib
  • Protein Serine-Threonine Kinases
  • Histone Deacetylases