[In-hospital ischemic strokes in patients admitted to Cardiology and Cardiac Surgery departments. Multi-centre registry]

Med Clin (Barc). 2011 Oct 22;137(11):479-83. doi: 10.1016/j.medcli.2011.02.033. Epub 2011 May 28.
[Article in Spanish]

Abstract

Background and objective: Patients admitted to Cardiology and Cardiac Surgery Departments have an increased risk of ischemic stroke (IS). We analyzed clinical characteristics, quality of neurological care and mortality of in-hospital strokes (IHS) in these departments.

Patients and method: Prospective registry of in-hospital ISs in Cardiology and Cardiac Surgery in 13 Spanish hospitals during 2008. Demographic, clinical and therapeutic data as well as mortality and functional evolution were recorded.

Results: 73 patients were included. Mean age was 72±11.6 years. 75.4% of IS were cardioembolic. Special risk factors were presence of cardiac sources of embolism (86.3%), prior withdrawal of antithrombotic treatment (22%) and invasive procedures (65.7%). First neurological assessment was done in the first 3hours in 49.5% and beyond 24hours from IS onset in 20.5%. Ten patients were treated with intravenous thrombolysis, which was not possible in 8 patients because of the delay in calling the neurologist. Most frequent reasons for exclusion from thrombolytic therapy were recent major surgical procedures (33.3%) and anticoagulant therapy (38%). Three-month mortality was 15% and only 53.7% were functionally independent. Patients treated with thrombolysis had a better evolution (87.5% of independent patients, p=0.04).

Conclusions: IS in Cardiology and Cardiac Surgery are mostly cardioembolic strokes and produce a high proportion of dependent patients. Patients treated with thrombolysis had a better evolution. Delays in contacting the neurologist led to exclusion from treatment an important proportion of patients who met thrombolysis criteria.

Publication types

  • English Abstract
  • Multicenter Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cardiology Service, Hospital / statistics & numerical data*
  • Coronary Vessels
  • Delayed Diagnosis
  • Diagnostic Techniques, Neurological
  • Embolism / complications
  • Female
  • Fibrinolytic Agents / therapeutic use
  • Hospital Mortality
  • Humans
  • Male
  • Prospective Studies
  • Registries
  • Risk Factors
  • Stroke* / diagnosis
  • Stroke* / drug therapy
  • Stroke* / etiology
  • Stroke* / mortality
  • Thrombolytic Therapy
  • Treatment Outcome

Substances

  • Fibrinolytic Agents