Abstract
Epidural cord compression from germ cell tumor metastases is not common. Treatment usually requires high dose corticosteroids with radiation therapy and/or surgical decompression. Three patients with epidural germ cell tumor metastases were treated with cisplatin-based chemotherapy and all three had complete neurologic recovery. Systemic chemotherapy should be considered as initial therapy with corticosteroids for epidural cord compression from metastatic germ cell tumor.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Carcinoma / complications
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Carcinoma / drug therapy
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Carcinoma / secondary*
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Dysgerminoma / complications
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Dysgerminoma / drug therapy
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Dysgerminoma / secondary*
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Humans
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Male
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Neoplasms, Germ Cell and Embryonal*
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Radiography
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Spinal Cord Compression / diagnostic imaging
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Spinal Cord Compression / drug therapy
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Spinal Cord Compression / etiology*
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Spinal Cord Neoplasms / complications
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Spinal Cord Neoplasms / drug therapy
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Spinal Cord Neoplasms / secondary*
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Testicular Neoplasms*