Transcription of genomic loci containing protein-coding genes often yields not only cognate mRNAs but also assorted non-coding RNAs (ncRNAs), which typically map in the vicinity of transcription start sites. A new study demonstrates that far from being random byproducts of gene expression, many long ncRNAs (lncRNAs) are synthesized in a coordinate fashion and control important cellular processes, such as survival in the face of DNA damage.