Multifunctional nanoparticles for targeted chemophotothermal treatment of cancer cells

Angew Chem Int Ed Engl. 2011 Aug 8;50(33):7581-6. doi: 10.1002/anie.201101783. Epub 2011 Jun 30.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Monoclonal, Humanized / chemistry
  • Antineoplastic Combined Chemotherapy Protocols / chemistry
  • Antineoplastic Combined Chemotherapy Protocols / pharmacology*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Apoptosis / drug effects
  • Cell Proliferation / drug effects
  • Dose-Response Relationship, Drug
  • Doxorubicin / chemistry
  • Doxorubicin / pharmacology
  • Female
  • Gold / chemistry
  • Hot Temperature*
  • Mammary Neoplasms, Experimental / pathology*
  • Mammary Neoplasms, Experimental / therapy*
  • Metal Nanoparticles / chemistry*
  • Mice
  • Mice, Inbred BALB C
  • Mice, Nude
  • Particle Size
  • Phototherapy*
  • Polyethylene Glycols / chemistry
  • Polyglactin 910 / chemistry
  • Structure-Activity Relationship
  • Surface Properties
  • Tissue Distribution
  • Trastuzumab
  • Xenograft Model Antitumor Assays

Substances

  • Antibodies, Monoclonal, Humanized
  • poly(lactic-glycolic acid)-poly(ethyleneglycol) copolymer
  • Polyglactin 910
  • Polyethylene Glycols
  • Gold
  • Doxorubicin
  • Trastuzumab