Clinical examination does not assist in the detection of systemic relapse of testicular germ cell tumour

Clin Oncol (R Coll Radiol). 2012 Feb;24(1):39-42. doi: 10.1016/j.clon.2011.06.002. Epub 2011 Jul 1.

Abstract

Aims: Patients on follow-up after orchidectomy or chemotherapy for testicular germ cell tumours follow a protocol of outpatient appointments and investigations designed to detect relapse. We wanted to investigate the contribution of clinical examination to patient management.

Materials and methods: The notes of 70 consecutive patients who suffered a first systemic relapse of their germ cell tumour within the last 10 years were studied to determine how the relapse was detected. Second testicular tumours were excluded.

Results: Of the 69 patients whose notes were available, only one had a significant finding on physical examination, concurrent with abnormal markers.

Conclusions: We suggest that, for patients following a planned programme of appointments and investigations, physical examination rarely contributes to the detection of systemic relapse in the follow-up of testicular germ cell tumours. It may therefore be possible to reconfigure follow-up to focus on investigations and telephone contact. We estimate that this change might be appropriate for 40% of attendances and might be welcomed by patients, many of whom find follow-up burdensome. If such a change were considered, patient education would be essential to ensure continuing compliance with the follow-up protocol.

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Humans
  • Male
  • Neoplasm Recurrence, Local / diagnosis*
  • Neoplasms, Germ Cell and Embryonal / diagnosis*
  • Neoplasms, Germ Cell and Embryonal / therapy
  • Orchiectomy
  • Physical Examination
  • Radiotherapy
  • Testicular Neoplasms / diagnosis*
  • Testicular Neoplasms / therapy

Substances

  • Antineoplastic Agents