Detection of respiratory chain dysfunction by measuring lactate and pyruvate production in cultured fibroblasts

J Inherit Metab Dis. 1990;13(3):355-8. doi: 10.1007/BF01799394.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Amino Acid Metabolism, Inborn Errors / diagnosis*
  • Cells, Cultured
  • Child, Preschool
  • Cytochrome-c Oxidase Deficiency
  • Fibroblasts / metabolism*
  • Humans
  • Infant, Newborn
  • Lactates / biosynthesis*
  • Lactic Acid
  • Mitochondria / enzymology*
  • Oxygen Consumption*
  • Pyruvates / metabolism*
  • Pyruvic Acid
  • Quinone Reductases / deficiency

Substances

  • Lactates
  • Pyruvates
  • Lactic Acid
  • Pyruvic Acid
  • NADH dehydrogenase (quinone)
  • Quinone Reductases