Severe docetaxel overdose induced by pharmacokinetic interaction with dronedarone

J Clin Oncol. 2011 Aug 20;29(24):e694-5. doi: 10.1200/JCO.2011.35.8002. Epub 2011 Jul 5.

Authors

Dominique Vodovar¹, Nicolas Mongardon, Laurence Moachon, Michel Arnaout, Philippe Beuzeboc, François Lokiec, Keyvan Rezai, Frédéric Pène

Affiliation

¹ Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.

PMID: 21730272
DOI: 10.1200/JCO.2011.35.8002

No abstract available

Publication types

Case Reports

MeSH terms

Aged
Amiodarone / adverse effects
Amiodarone / analogs & derivatives*
Anti-Arrhythmia Agents / adverse effects*
Antineoplastic Agents / adverse effects*
Antineoplastic Agents / pharmacokinetics
Atrial Fibrillation / chemically induced
Atrial Fibrillation / drug therapy*
Docetaxel
Dronedarone
Drug Administration Schedule
Drug Overdose
Fatal Outcome
Humans
Male
Mucositis / chemically induced*
Prostatic Neoplasms / drug therapy*
Taxoids / adverse effects*
Taxoids / pharmacokinetics

Substances

Anti-Arrhythmia Agents
Antineoplastic Agents
Taxoids
Docetaxel
Dronedarone
Amiodarone