Endoscopic ultrasound in patients over 80 years old

Dig Dis Sci. 2011 Oct;56(10):3065-71. doi: 10.1007/s10620-011-1718-7. Epub 2011 Jul 7.

Abstract

Background: The data on the safety and utility of EUS in patients over 80 years of age is limited.

Objective: We investigated the indications, feasibility, safety, and clinical utility of EUS in the management of GI, pancreatobiliary, and mediastinal diseases.

Design: Retrospective study.

Setting: A tertiary referral university hospital.

Patients: Consecutive patients ≥80 years of age referred over a 9-year period for EUS evaluation.

Results: A total of 265 EUS scans were performed in 232 patients with a mean age of 83.8 years. The indications for pancreatobiliary EUS were to evaluate a pancreatic mass (n = 60), pancreatic cyst (n = 18), pancreatitis (n = 10), dilated CBD in the setting of jaundice and/or biliary stricture (n = 20), dilated CBD with no jaundice and/or biliary stricture (n = 20). The indications for luminal gastrointestinal EUS were esophageal lesions (n = 21), gastric lesions (n = 30), duodenal lesions (n = 14), rectal lesions (n = 22), and gastrointestinal subepithelial lesions (n = 28). The indications for mediastinal EUS were mass/lymphadenopathy (n = 14). EUS-guided FNA (EUS-FNA) was performed in 95 (35.8%) cases and results were consistent or suspicious for a malignancy in 62 cases (65.2%). Endoscopic mucosal resection (EMR) was performed in 17 cases (6.41%) on the same session following endosonographic evaluation. The procedure was successful in all patients with no complications related to sedation, EUS, or EUS-FNA encountered. One patient had perforation following EMR.

Limitation: Retrospective study.

Conclusions: EUS and EUS-FNA are feasible and safe and have a significant impact on the management of GI, pancreatobiliary and mediastinal diseases in extreme elderly.

MeSH terms

  • Age Factors
  • Aged, 80 and over
  • Biopsy, Fine-Needle / adverse effects
  • Biopsy, Fine-Needle / methods
  • Endosonography / adverse effects
  • Endosonography / methods*
  • Feasibility Studies
  • Female
  • Gastrointestinal Diseases / diagnostic imaging*
  • Humans
  • Male
  • Mediastinal Diseases / diagnostic imaging*
  • Pancreatic Diseases / diagnostic imaging*
  • Retrospective Studies
  • Sensitivity and Specificity