Di-tert-butylisobutylsilyl, another useful protecting group

Huan Liang; Lin Hu; E J Corey

doi:10.1021/ol201640y

Di-tert-butylisobutylsilyl, another useful protecting group

Org Lett. 2011 Aug 5;13(15):4120-3. doi: 10.1021/ol201640y. Epub 2011 Jul 11.

Authors

Huan Liang¹, Lin Hu, E J Corey

Affiliation

¹ Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.

PMID: 21744824
DOI: 10.1021/ol201640y

Abstract

The di-tert-butylisobutylsilyl (BIBS) protecting group offers new possibilities for synthetic processes because of its steric bulk, robustness of its derivatives, and other special properties.