Anti-galactose-α-1,3-galactose IgE from allergic patients does not bind α-galactosylated glycans on intact therapeutic antibody Fc domains

Nat Biotechnol. 2011 Jul 11;29(7):574-6. doi: 10.1038/nbt.1912.
No abstract available

Publication types

  • Letter

MeSH terms

  • Disaccharides / immunology*
  • Humans
  • Hypersensitivity / enzymology*
  • Hypersensitivity / immunology*
  • Immunoglobulin E / immunology*
  • Immunoglobulin Fc Fragments / immunology*
  • Immunoglobulin Fc Fragments / therapeutic use*
  • Immunoglobulin Fragments / immunology*
  • Protein Binding

Substances

  • Disaccharides
  • Immunoglobulin Fc Fragments
  • Immunoglobulin Fragments
  • galactosyl-(1-3)galactose
  • Immunoglobulin E