Abstract
Of 176 invasive Streptococcus pneumoniae isolates from children in Malawi, common serotypes were 1 (23%), 6A/B (18%), 14 (6%), and 23F (6%). Coverage with the 7-valent pneumococcal conjugate vaccine (PCV) was 39%; PCV10 and PCV13 increased coverage to 66% and 88%, respectively. We found chloramphenicol resistance in 27% of isolates and penicillin nonsusceptibility in 10% (by using meningitis breakpoints); all were ceftriaxone susceptible.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Adolescent
-
Anti-Bacterial Agents / pharmacology
-
Child
-
Child, Preschool
-
Drug Resistance, Bacterial
-
Female
-
HIV Infections / complications
-
Humans
-
Infant
-
Male
-
Microbial Sensitivity Tests
-
Pneumococcal Infections / diagnosis
-
Pneumococcal Infections / microbiology*
-
Pneumococcal Infections / mortality
-
Serotyping
-
Streptococcus pneumoniae / classification
-
Streptococcus pneumoniae / drug effects
-
Streptococcus pneumoniae / isolation & purification
-
Streptococcus pneumoniae / physiology*