The complete genome sequence of an enterovirus 76 isolate in China reveals a recombination event

Arch Virol. 2011 Sep;156(9):1685-9. doi: 10.1007/s00705-011-1067-z. Epub 2011 Jul 14.

Abstract

Enterovirus 76 (EV76) is a new member of species Human Enterovirus A (HEV-A). So far, the only complete genome sequence of the prototype strain from France has been available. In this study, we determined the complete nucleotide sequence of strain 04360, isolated from an acute flaccid paralysis patient in Shandong province, China in 2004. Sequence analysis revealed 80.7-94.7% VP1 nucleotide identity to other EV76 strains and provided evidence of recombination with other types of HEV-A in the P2 and P3 coding regions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • China / epidemiology
  • Enterovirus / genetics*
  • Enterovirus Infections / epidemiology
  • Enterovirus Infections / virology*
  • Genome, Viral*
  • Humans
  • Molecular Sequence Data
  • Phylogeny
  • Reassortant Viruses / genetics*

Associated data

  • GENBANK/GQ253424
  • GENBANK/GQ253425
  • GENBANK/JF905564