Abstract
For the first time in Argentina, we describe an outbreak of contact dermatitis. New pairs of shoes caused intense pruritus, pain, and eruption, followed by edema, blisters, and a severe negative impact on the epidermal barrier of the feet. We identify dimethylfumarate as the causal agent and suggest an analytical method for its fast identification.
MeSH terms
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Adult
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Animals
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Anti-Bacterial Agents / therapeutic use
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Argentina
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Blister / etiology
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Blister / pathology
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Dermatitis, Contact / etiology*
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Dermatitis, Contact / pathology
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Dimethyl Fumarate
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Epidemics
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Erythema / pathology
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Female
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Foot / pathology*
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Fumarates / adverse effects*
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Fungicides, Industrial / adverse effects*
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Fungicides, Industrial / therapeutic use
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Gentamicins / therapeutic use
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Humans
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Hypersensitivity / diagnosis
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Miconazole / therapeutic use
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Patch Tests
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Pruritus / pathology
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Rabbits
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Shoes
Substances
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Anti-Bacterial Agents
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Fumarates
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Fungicides, Industrial
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Gentamicins
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Miconazole
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Dimethyl Fumarate