Abstract
Lung is one of the main sites of metastatic tumors, but collision neoplasms consisting of a primary lung cancer and metastatic breast carcinoma have never been so far reported. We describe here 2 cases of primary non-small cell lung cancers (squamous cell and adenocarcinoma, respectively) colliding with metastatic breast carcinomas (ductal and lobular carcinomas, respectively). Clinico-pathologic features characterizing this challenging diagnosis and the important therapeutic implications are discussed.
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
MeSH terms
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Adenocarcinoma / diagnosis*
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Adenocarcinoma / pathology
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Adenocarcinoma / physiopathology
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Adenocarcinoma / therapy
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Aged
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Animals
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Breast Neoplasms / diagnosis*
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Breast Neoplasms / pathology
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Breast Neoplasms / physiopathology
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Breast Neoplasms / therapy
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Carcinoma, Ductal / diagnosis*
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Carcinoma, Ductal / physiopathology
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Carcinoma, Ductal / secondary
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Carcinoma, Ductal / therapy
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Carcinoma, Lobular / diagnosis*
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Carcinoma, Lobular / physiopathology
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Carcinoma, Lobular / secondary
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Carcinoma, Lobular / therapy
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Carcinoma, Squamous Cell / diagnosis*
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Carcinoma, Squamous Cell / pathology
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Carcinoma, Squamous Cell / physiopathology
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Carcinoma, Squamous Cell / therapy
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Chemoradiotherapy, Adjuvant
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Diagnosis, Differential
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Female
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Humans
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Lung Neoplasms / diagnosis*
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Lung Neoplasms / pathology
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Lung Neoplasms / physiopathology
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Lung Neoplasms / secondary*
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Mastectomy
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Middle Aged
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Neoplasm Staging
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Pathology, Molecular
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Pneumonectomy
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Remission Induction