Higher rate of bronchoalveolar lavage culture positivity in children with nonacid reflux and respiratory disorders

J Pediatr. 2011 Sep;159(3):504-6. doi: 10.1016/j.jpeds.2011.05.021. Epub 2011 Jul 21.

Abstract

The aim of the study was to determine if children with chronic cough or wheezing and with more full-column, nonacid reflux have a higher likelihood of a positive bronchoalveolar lavage fluid culture. In a prospective study of 46 children with cough who were undergoing endoscopy, multichannel intraluminal impedance testing, and bronchoscopy, we found that patients who had a positive culture had significantly more full-column, nonacid gastroesophageal reflux than those who had a negative culture.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Bronchoalveolar Lavage
  • Bronchoalveolar Lavage Fluid / microbiology*
  • Child
  • Child, Preschool
  • Cough / epidemiology*
  • Cross-Sectional Studies
  • Electric Impedance
  • Esophageal pH Monitoring
  • Esophagitis / epidemiology
  • Gastroesophageal Reflux / epidemiology*
  • Humans
  • Prospective Studies
  • Respiratory Sounds*