Simultaneous necrotizing glomerulonephritis and Hodgkin's lymphoma: a case report and review of the literature

Nephrol Dial Transplant. 2011 Oct;26(10):3403-8. doi: 10.1093/ndt/gfr394. Epub 2011 Jul 21.

Abstract

Glomerulonephritis occurs in 1% of Hodgkin's lymphoma patients. In the even rarer setting of rapidly progressive glomerulonephritis, lymphoma may go unrecognized. We describe a case of necrotizing glomerulonephritis in which treatment with cyclophosphamide and steroids led to resolution of lymphadenopathy. Two years later, recrudescent lymphadenopathy was shown to be Hodgkin's lymphoma, but renal disease did not recur.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cyclophosphamide / administration & dosage
  • Diagnosis, Differential
  • Female
  • Glomerulonephritis / complications*
  • Glomerulonephritis / diagnosis*
  • Glomerulonephritis / drug therapy
  • Hodgkin Disease / complications*
  • Hodgkin Disease / diagnosis*
  • Hodgkin Disease / drug therapy
  • Humans
  • Prednisolone / administration & dosage
  • Prognosis

Substances

  • Cyclophosphamide
  • Prednisolone