Late-onset Klebsiella oxytoca flap-margin-related corneal ulcer following laser in situ keratomileusis

J Cataract Refract Surg. 2011 Aug;37(8):1551-4. doi: 10.1016/j.jcrs.2011.05.016.

Abstract

A 45-year-old woman developed a spontaneous flap-margin-related corneal ulcer 11 years after the original laser in situ keratomileusis (LASIK) procedure. Two enhancements had been performed; the most recent was 3 years prior to presentation. Cultures were positive for a heavy growth of Klebsiella oxytoca. The ulcer responded clinically to topical treatment with fortified cefazolin. Eighteen days after presentation, the infiltrate had resolved and the cornea had fully epithelialized. To our knowledge, this is the first report of post-LASIK infectious keratitis caused by K oxytoca.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Cefazolin / therapeutic use
  • Corneal Topography
  • Corneal Ulcer / diagnosis
  • Corneal Ulcer / drug therapy
  • Corneal Ulcer / microbiology*
  • Eye Infections, Bacterial / diagnosis
  • Eye Infections, Bacterial / drug therapy
  • Eye Infections, Bacterial / microbiology*
  • Female
  • Humans
  • Keratomileusis, Laser In Situ*
  • Klebsiella Infections / diagnosis
  • Klebsiella Infections / drug therapy
  • Klebsiella Infections / microbiology*
  • Klebsiella oxytoca / isolation & purification*
  • Middle Aged
  • Surgical Flaps / microbiology*
  • Surgical Wound Infection / diagnosis
  • Surgical Wound Infection / drug therapy
  • Surgical Wound Infection / microbiology*

Substances

  • Anti-Bacterial Agents
  • Cefazolin