Abstract
An upstream ORF cooperates with Sex lethal to inhibit msl-2 translation during Drosophila sex determination, a biological principle with potentially broad application in gene regulation.
MeSH terms
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Animals
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DNA-Binding Proteins / genetics*
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Drosophila / genetics
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Drosophila / metabolism
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Drosophila Proteins / genetics*
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Epistasis, Genetic
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Nuclear Proteins / genetics*
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Open Reading Frames*
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Protein Biosynthesis
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RNA, Messenger / metabolism*
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RNA-Binding Proteins / genetics*
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Ribosomes / metabolism*
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Transcription Factors / genetics*
Substances
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DNA-Binding Proteins
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Drosophila Proteins
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Nuclear Proteins
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RNA, Messenger
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RNA-Binding Proteins
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Sxl protein, Drosophila
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Transcription Factors
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msl-2 protein, Drosophila