Repeat partial nephrectomy: surgical, functional and oncological outcomes

Curr Opin Urol. 2011 Sep;21(5):368-75. doi: 10.1097/MOU.0b013e32834964ea.

Abstract

Purpose of review: The greater utilization of partial nephrectomy and ablative procedures has increased the incidence of patients presenting with local renal recurrence. The choice to either perform a partial or radical nephrectomy in these situations can be a challenging decision.

Recent findings: Repeat and salvage partial nephrectomy, while challenging and potentially associated with increased complications, offers patients the ability to maintain excellent renal functional outcomes and promising oncologic outcomes at intermediate follow-up.

Summary: Surgeons should be familiar with the surgical complications and the functional and oncologic outcomes of reoperative nephron-sparing surgery (NSS). Recent data and outcome analysis support utilization of these procedures in patients presenting with either local recurrence or de-novo lesions in the ipsilateral kidney.

Publication types

  • Research Support, N.I.H., Intramural
  • Review

MeSH terms

  • Humans
  • Kidney / physiology*
  • Kidney / surgery
  • Kidney Diseases / diagnosis*
  • Kidney Diseases / surgery*
  • Kidney Neoplasms / prevention & control
  • Kidney Neoplasms / surgery
  • Neoplasm Recurrence, Local / prevention & control
  • Nephrectomy / methods*
  • Prognosis
  • Reoperation / methods
  • Salvage Therapy / methods