Longitudinal characterization of Acinetobacter baumannii-calcoaceticus complex, Klebsiella pneumoniae, and methicillin-resistant Staphylococcus aureus colonizing and infecting combat casualties

Am J Infect Control. 2012 Mar;40(2):183-5. doi: 10.1016/j.ajic.2011.03.025. Epub 2011 Jul 28.

Abstract

Drug-resistant Acinetobacter baumannii-calcoaceticus complex, Klebsiella pneumoniae, and methicillin-resistant Staphylococcus aureus colonize and infect combat casualties from Iraq and Afghanistan. We retrospectively evaluated relatedness, by pulsed-field gel electrophoresis and antibiotic susceptibility testing, of isolates colonizing and infecting casualties over 2 years. Colonizing organisms were unrelated to isolates producing later infection in up to 27% of cases; most isolates underwent change in antibiotic susceptibilities. The same is true for serial infecting isolates recovered during hospitalization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter baumannii / genetics*
  • Acinetobacter baumannii / isolation & purification
  • Acinetobacter calcoaceticus / genetics*
  • Acinetobacter calcoaceticus / isolation & purification
  • Afghan Campaign 2001-
  • Bacterial Typing Techniques
  • Cross Infection / drug therapy
  • Cross Infection / microbiology*
  • Drug Resistance, Multiple, Bacterial / genetics*
  • Electrophoresis, Gel, Pulsed-Field
  • Hospitals, Military
  • Humans
  • Iraq War, 2003-2011
  • Klebsiella pneumoniae / genetics*
  • Klebsiella pneumoniae / isolation & purification
  • Longitudinal Studies
  • Methicillin-Resistant Staphylococcus aureus / genetics*
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification
  • Microbial Sensitivity Tests
  • Military Personnel*
  • Retrospective Studies
  • United States
  • Wounds and Injuries / drug therapy
  • Wounds and Injuries / microbiology*