Cyto-reductive Surgery combined with Hyperthermic Intra-peritoneal Chemotherapy for Peritoneal Surface Malignancies: current treatment and results

Antonio Sommariva; Pierluigi Pilati; Carlo Riccardo Rossi

doi:10.1016/j.ctrv.2011.07.001

Cyto-reductive Surgery combined with Hyperthermic Intra-peritoneal Chemotherapy for Peritoneal Surface Malignancies: current treatment and results

Cancer Treat Rev. 2012 Jun;38(4):258-68. doi: 10.1016/j.ctrv.2011.07.001. Epub 2011 Jul 31.

Authors

Antonio Sommariva¹, Pierluigi Pilati, Carlo Riccardo Rossi

Affiliation

¹ Melanoma and Sarcoma Unit, Veneto Institute of Oncology, National Cancer Institute - IRCCS, Padova, Italy. [email protected]

PMID: 21807464
DOI: 10.1016/j.ctrv.2011.07.001

Abstract

Cyto-reductive Surgery (CS) combined with Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) as loco-regional treatment of Peritoneal Surface Malignancies (PSM) has increasingly gained acceptance in clinical practice. This review summarizes the more relevant studies on this topic. Indications, pre-operative work-up, technical aspects, outcome and future directions of this combined approach in the treatment of Peritoneal Surface Malignancies are discussed here and proposed in an informative and didactic manner.

MeSH terms

Antineoplastic Agents / therapeutic use*
Combined Modality Therapy
Humans
Hyperthermia, Induced / methods
Peritoneal Neoplasms / drug therapy
Peritoneal Neoplasms / surgery
Peritoneal Neoplasms / therapy*

Substances

Antineoplastic Agents