Purpose: To identify factors correlated with poor outcome and factors correlated with acute kidney injury (AKI) onset in critically A(H1N1) infected patients.
Methods: All patients admitted for respiratory distress due to a confirmed infection by A(H1N1) virus were included retrospectively.
Results: Thirty-four patients were included. Mean age was 37.3 ± 20.8 years. Independent factors correlated to mortality in multivariate analysis were shock [OR = 32.52, CI95% (1.29-816.3); p = 0.034], AKI [OR = 31.12, CI95% (1.3-746.5); p = 0.034] and hyperglycaemia over than 5.7 mmol/l on admission [OR = 74, CI95% (1.01-5495); p = 0.049]. Only age over 30 years was identified as an independent factor correlated with the onset of AKI [OR = 18, CI95% (1.04-312.41); p = 0.047] in multivariate analysis.
Conclusion: AKI, as well as hypotension, is an independent factor correlated with mortality. Its onset is usually linked to multi-organ failure. Advanced age is an important risk factor for renal dysfunction in this group of patients.
© 2011 European Dialysis and Transplant Nurses Association/European Renal Care Association.