Partial recovery from amnesia following bilateral surgical fornix transection is correlated with cortical plasticity

N K Mazarakis; F Summers; A D Murray; G D Waiter; I P Fouyas

doi:10.3109/02688697.2011.584982

Partial recovery from amnesia following bilateral surgical fornix transection is correlated with cortical plasticity

Br J Neurosurg. 2011 Oct;25(5):658-61. doi: 10.3109/02688697.2011.584982. Epub 2011 Aug 4.

Authors

N K Mazarakis¹, F Summers, A D Murray, G D Waiter, I P Fouyas

Affiliation

¹ Department of Neurosurgery, Queen's Medical Centre, Nottingham, UK. [email protected]

PMID: 21815737
DOI: 10.3109/02688697.2011.584982

Abstract

We report a case of an interventricular ependymoma which was surgically removed but also required bilateral transection of the fornices resulting in memory impairment which gradually improved. Functional MR images using a memory paradigm showed that recovery correlated with cortical plasticity involving activation of the orbitofrontal cortex and the middle temporal gyrus.

Publication types

Case Reports

MeSH terms

Adult
Amnesia / etiology*
Amnesia / physiopathology
Cerebral Ventricle Neoplasms / diagnostic imaging
Cerebral Ventricle Neoplasms / surgery*
Ependymoma / diagnostic imaging
Ependymoma / surgery*
Fornix, Brain / injuries
Humans
Magnetic Resonance Imaging
Male
Neuronal Plasticity*
Neuropsychological Tests
Postoperative Complications*
Prefrontal Cortex / physiology
Radiography
Recovery of Function
Treatment Outcome