Abstract
Meningiomas are slow-growing benign tumors believed to originate from arachnoidal cap cells. This article discusses the surgical approaches for resection, especially the transnasal endoscopic approach. Alternative treatment options are primarily used where patients are not surgical candidates or location of recurrence precludes additional surgery. These options include radiotherapy, stereotactic radiosurgery, and chemotherapy. In addition, we discuss the current on going research in molecular targeting agents for meningioma treatment.
Copyright © 2011 Elsevier Inc. All rights reserved.
MeSH terms
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Antineoplastic Agents / therapeutic use*
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Clinical Trials as Topic
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Combined Modality Therapy
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Endoscopy* / adverse effects
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Endoscopy* / methods
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Humans
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Meningeal Neoplasms / diagnosis
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Meningeal Neoplasms / etiology
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Meningeal Neoplasms / mortality
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Meningeal Neoplasms / therapy
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Meningioma / diagnosis
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Meningioma / etiology
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Meningioma / mortality
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Meningioma / therapy*
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Minimally Invasive Surgical Procedures
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Molecular Targeted Therapy
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Patient Selection
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Radiation, Ionizing
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Radiosurgery* / adverse effects
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Radiosurgery* / methods
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Radiotherapy*
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Recurrence
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Risk Factors
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Survival Rate
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Treatment Outcome