Congenital melanocytic nevi with halo phenomenon: report of two cases and a review of the literature

J Dermatol Surg Oncol. 1990 Apr;16(4):377-80. doi: 10.1111/j.1524-4725.1990.tb00051.x.

Abstract

Verrucous congenital nevocellular nevi surrounded by a depigmented halo occurring in a 7-year-old boy and a 13-year-old girl were excised and the wounds closed primarily. Histopathologic studies revealed a striking arrangement of the inflammatory infiltrate in these halo nevi. A dense, band-like, lymphohistiocytic infiltrate was found only around and intermingled with A- and B-type nevomelanocytes in the upper dermis, whereas inflammatory infiltrates were completely absent from type C-nevomelanocytes in the lower parts of the reticular dermis. The literature is reviewed with particular consideration of congenital halo nevi.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Melanins
  • Melanocytes / pathology
  • Neoplasms, Multiple Primary / congenital*
  • Neoplasms, Multiple Primary / pathology
  • Nevus / congenital*
  • Nevus / pathology
  • Nevus, Pigmented / congenital*
  • Nevus, Pigmented / pathology
  • Skin Neoplasms / congenital*
  • Skin Neoplasms / pathology

Substances

  • Melanins