Bacterial, fungal, and algal lectins: combatants in tug of war against HIV

Ten Feizi; Yan Liu; Angelina S Palma

doi:10.1016/j.str.2011.07.006

Bacterial, fungal, and algal lectins: combatants in tug of war against HIV

Structure. 2011 Aug 10;19(8):1035-7. doi: 10.1016/j.str.2011.07.006.

Authors

Ten Feizi¹, Yan Liu, Angelina S Palma

Affiliation

¹ The Glycosciences Laboratory, Imperial College London, Burlington Danes Building Level 5, Du Cane Road, London, W12 0NN, UK. [email protected]

PMID: 21827940
DOI: 10.1016/j.str.2011.07.006

Abstract

High-resolution X-ray crystallography and NMR studies by Koharudin and Gronenborn in this issue provide new information on the mode of N-glycan recognition by a cyanobacterial agglutinin, with anti-HIV activity pointing to the pentamannosyl core as a novel target for therapeutic intervention.

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