Successful radiopeptide targeting of metastatic anaplastic meningioma: case report

Radiat Oncol. 2011 Aug 12:6:94. doi: 10.1186/1748-717X-6-94.

Abstract

A patient with anaplastic meningioma and lung metastases resistant to conventional treatment underwent radiopeptide therapy with 177Lu- DOTA-octreotate in our institute. The treatment resulted in significant improvement in patient's quality of life and inhibition of tumor progression. This case may eventually help to establish the value of radiopeptide therapy in patients with this rare condition.

Publication types

  • Case Reports

MeSH terms

  • Blood-Brain Barrier
  • Coordination Complexes / pharmacology
  • Disease Progression
  • Female
  • Humans
  • Lung Neoplasms / pathology
  • Lung Neoplasms / secondary
  • Meningioma / pathology
  • Meningioma / radiotherapy*
  • Middle Aged
  • Neoplasm Metastasis
  • Octreotide / analogs & derivatives
  • Octreotide / pharmacology
  • Positron-Emission Tomography / methods
  • Quality of Life
  • Radiopharmaceuticals / pharmacology
  • Receptors, Peptide / chemistry
  • Tomography, Emission-Computed, Single-Photon / methods
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome

Substances

  • 177Lu-DOTA-octreotate
  • 177Lu-octreotide, DOTA(0)-Tyr(3)-
  • Coordination Complexes
  • Radiopharmaceuticals
  • Receptors, Peptide
  • Octreotide