Facile functionalization of a fully fluorescent perfluorophenyl BODIPY: photostable thiol and amine conjugates

Chem Commun (Camb). 2011 Oct 7;47(37):10425-7. doi: 10.1039/c1cc13778f. Epub 2011 Aug 19.

Abstract

Selective nucleophilic substitution on a perfluorophenyl unit comprising a BODIPY fluorophore using an alkanethiol or a primary amine offers a quantitative fluorophore labelling strategy, while retaining high photostability and emission quantum yields approaching unity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amines / chemistry*
  • Boron Compounds / chemistry*
  • Fluorescent Dyes / chemistry*
  • Hydrocarbons, Fluorinated / chemistry*
  • Spectrometry, Fluorescence
  • Sulfhydryl Compounds / chemistry*

Substances

  • 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
  • Amines
  • Boron Compounds
  • Fluorescent Dyes
  • Hydrocarbons, Fluorinated
  • Sulfhydryl Compounds