Background: Liver disease is an increasing cause of morbidity and mortality in Human immunodeficiency virus (HIV) positive patients.
Aim: To describe the first cases of organ transplantation in HIV positive patients in Ireland.
Method: We report the Irish patients with HIV who received liver transplantation and performed a chart review.
Result: Two patients received liver transplantation for end stage liver disease caused by Hepatitis C, with survival at 2 years of 100%.
Conclusion: Liver transplantation is a feasible treatment for patients with HIV and end stage liver disease. The success of transplantation in the HIV positive population should encourage the provision of other medical and surgical interventions previously not offered to patients with HIV.