Sequential SPECT and optical imaging of experimental models of prostate cancer with a dual modality inhibitor of the prostate-specific membrane antigen

Angew Chem Int Ed Engl. 2011 Sep 19;50(39):9167-70. doi: 10.1002/anie.201102872. Epub 2011 Aug 22.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Fluorescent Dyes / chemistry
  • Heterocyclic Compounds, 1-Ring / chemistry
  • Indium Radioisotopes / chemistry
  • Male
  • Mice
  • Peptides / chemistry
  • Peptides / pharmacokinetics
  • Porphyrins / chemistry*
  • Porphyrins / pharmacokinetics
  • Prostate-Specific Antigen / antagonists & inhibitors*
  • Prostate-Specific Antigen / metabolism
  • Prostatic Neoplasms / diagnostic imaging*
  • Protease Inhibitors / chemistry*
  • Protease Inhibitors / pharmacokinetics
  • Tissue Distribution
  • Tomography, Emission-Computed, Single-Photon
  • Transplantation, Heterologous

Substances

  • Fluorescent Dyes
  • Heterocyclic Compounds, 1-Ring
  • Indium Radioisotopes
  • Peptides
  • Porphyrins
  • Protease Inhibitors
  • 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid
  • Prostate-Specific Antigen