Risk factors for bacteraemia attributable to Pseudomonas aeruginosa resistant to imipenem, levofloxacin, or gentamicin

J Hosp Infect. 2011 Nov;79(3):267-8. doi: 10.1016/j.jhin.2011.07.003. Epub 2011 Aug 24.

Abstract

We studied the risk factors associated with resistance to imipenem, levofloxacin and gentamicin in Pseudomonas aeruginosa isolated from blood cultures of 175 patients in a hospital in Japan. Imipenem resistance was associated with transfer from another hospital, and receiving antifungal medication. Gentamicin resistance was associated with previous administration of a penicillin. No specific risk factors were associated with levofloxacin resistance.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / pharmacology*
  • Bacteremia / microbiology*
  • Child
  • Child, Preschool
  • Drug Resistance, Multiple, Bacterial*
  • Female
  • Gentamicins / pharmacology*
  • Gentamicins / therapeutic use
  • Humans
  • Imipenem / pharmacology*
  • Imipenem / therapeutic use
  • Infant
  • Infant, Newborn
  • Levofloxacin*
  • Male
  • Middle Aged
  • Ofloxacin / pharmacology*
  • Ofloxacin / therapeutic use
  • Pseudomonas Infections / microbiology
  • Pseudomonas aeruginosa / drug effects*
  • Pseudomonas aeruginosa / isolation & purification
  • Risk Factors
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Gentamicins
  • Levofloxacin
  • Imipenem
  • Ofloxacin