Unique features of obstructive sleep apnea in World Trade Center responders with aerodigestive disorders

J Occup Environ Med. 2011 Sep;53(9):975-80. doi: 10.1097/JOM.0b013e3182305282.

Abstract

Objectives: To compare obstructive sleep apnea (OSA) in World Trade Center (WTC) responders with aerodigestive disorders and snoring with non-WTC habitual snorers, and to distinguish features of OSA in a subset of responders with worsening of snoring after 9/11 from responders with previous habitual snoring.

Methods: Cross-sectional comparative study of 50 WTC Medical Monitoring and Treatment Program responders with aerodigestive disorders and snoring and 50 nonresponders with snoring. Responders with worsening of snoring after 9/11 were compared with previous habitual snorers.

Results: : While there was a strong correlation between body mass index (BMI), weight, and Apnea + Hypopnea Index (r = 0.36, P = 0.001; r = 0.29, P = 0.044) in the nonresponders, no correlation between either BMI or weight and Apnea + Hypopnea Index was found in the responders. Responders with worsening of snoring after 9/11 had a significantly lower BMI than previous habitual snorers.

Conclusion: Mechanisms other than obesity are important in the pathogenesis of OSA in WTC responders with aerodigestive disorders.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Body Mass Index
  • Body Weight
  • Cross-Sectional Studies
  • Disease Progression
  • Dust*
  • Emergency Medical Services
  • Gastroesophageal Reflux / complications
  • Humans
  • Inhalation Exposure / adverse effects*
  • Middle Aged
  • Occupational Exposure / adverse effects*
  • Rescue Work*
  • September 11 Terrorist Attacks*
  • Severity of Illness Index
  • Sleep Apnea, Obstructive / complications
  • Sleep Apnea, Obstructive / etiology*
  • Snoring / complications

Substances

  • Dust