Critical role for programmed death 1 signaling and protein kinase B in augmented regulatory T-cell induction in cord blood

J Allergy Clin Immunol. 2011 Dec;128(6):1369-71. doi: 10.1016/j.jaci.2011.08.006. Epub 2011 Aug 25.

Authors

Sytze de Roock, Sanne B E A Hoeks, Linda Meurs, Anouk Steur, Maarten O Hoekstra, Berent J Prakken, Marianne Boes, Ismé M de Kleer

PMID: 21868077
DOI: 10.1016/j.jaci.2011.08.006

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cell Differentiation / immunology
Fetal Blood / immunology*
Humans
Infant, Newborn
Lymphocyte Activation / immunology
Programmed Cell Death 1 Receptor / immunology*
Proto-Oncogene Proteins c-akt / immunology*
Self Tolerance / immunology*
Signal Transduction / immunology*
T-Lymphocyte Subsets / cytology
T-Lymphocyte Subsets / immunology
T-Lymphocytes, Regulatory / cytology
T-Lymphocytes, Regulatory / immunology*

Substances

PDCD1 protein, human
Programmed Cell Death 1 Receptor
Proto-Oncogene Proteins c-akt