Pure erythroid leukemia following precursor B-cell lymphoblastic leukemia

Pediatr Dev Pathol. 2012 Jan-Feb;15(1):76-8. doi: 10.2350/11-04-1029-CR.1. Epub 2011 Aug 30.

Abstract

Therapy-related acute myeloid leukemia is an unfortunate sequel to current multimodal intensive chemotherapy. The patient described was diagnosed with pure erythroleukemia, AML-M6b, during therapy for precursor B-cell acute lymphoblastic leukemia. To the best of our knowledge, this is the first report of this unusual association.

Publication types

  • Case Reports

MeSH terms

  • Abnormal Karyotype
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bone Marrow Cells / pathology
  • Child
  • Clone Cells
  • Fatal Outcome
  • Female
  • Humans
  • Immunophenotyping
  • In Situ Hybridization, Fluorescence
  • Leukemia, Erythroblastic, Acute / diagnosis*
  • Leukemia, Erythroblastic, Acute / drug therapy
  • Leukemia, Erythroblastic, Acute / genetics
  • Neoplasms, Second Primary / diagnosis*
  • Neoplasms, Second Primary / drug therapy
  • Neoplasms, Second Primary / genetics
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / genetics