Effectiveness of antibiotic-lock therapy for long-term catheter-related bacteremia due to Gram-negative bacilli: a prospective observational study

Clin Infect Dis. 2011 Nov;53(9):e129-32. doi: 10.1093/cid/cir551. Epub 2011 Sep 2.

Abstract

A prospective observational study evaluated the effectiveness of combining antibiotic-lock therapy and systemic antibiotics for Gram-negative bacilli long-term catheter-related bacteremia. In 46 uncomplicated episodes, the most frequently isolated microorganisms were Pseudomonas aeruginosa (15), Enterobacter cloacae (12), Escherichia coli (10), and Klebsiella spp. (8). Cure was achieved in 95% of cases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / administration & dosage*
  • Bacteremia / drug therapy*
  • Bacteremia / microbiology
  • Catheter-Related Infections / drug therapy*
  • Catheter-Related Infections / microbiology
  • Cohort Studies
  • Female
  • Gram-Negative Bacteria / classification
  • Gram-Negative Bacteria / isolation & purification
  • Gram-Negative Bacterial Infections / drug therapy*
  • Gram-Negative Bacterial Infections / microbiology
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents