Palladium-catalyzed amination of allyl alcohols

J Org Chem. 2011 Oct 21;76(20):8508-12. doi: 10.1021/jo2014438. Epub 2011 Sep 21.

Abstract

An efficient catalytic amination of aryl-substituted allylic alcohols has been developed. The complex [(η(3)-allyl)PdCl](2) modified by a bis phosphine ligand, L, has been used as catalyst in the reaction that afforded a wide range of allyl amines in good to excellent yield under mild conditions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Allyl Compounds / chemical synthesis*
  • Amination
  • Amines / chemical synthesis*
  • Biological Products / chemical synthesis*
  • Catalysis
  • Chemistry, Pharmaceutical / methods*
  • Ligands
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Palladium / chemistry
  • Phosphines / chemistry*
  • Propanols / chemistry*
  • Stereoisomerism

Substances

  • Allyl Compounds
  • Amines
  • Biological Products
  • Ligands
  • Phosphines
  • Propanols
  • allyl alcohol
  • Palladium
  • phosphine