Abstract
Locally acquired hepatitis E infection is increasingly being observed in industrialized countries. We report 2 cases of autochthonous acute hepatitis E in the United States. Hepatitis E virus genotype 3a related to US-2 and swine hepatitis E virus strains was isolated from one of the patients, indicating potential food-borne or zoonotic transmission.
MeSH terms
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Adult
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Animals
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Disease Reservoirs
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Fatal Outcome
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Female
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Foodborne Diseases
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Genome, Viral / genetics
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Genotype
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Hepatitis Antibodies / blood*
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Hepatitis E / diagnosis*
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Hepatitis E / transmission
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Hepatitis E / virology
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Hepatitis E virus / genetics
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Hepatitis E virus / immunology*
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Hepatitis E virus / isolation & purification
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Humans
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Phylogeny
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RNA, Viral / genetics
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Retrospective Studies
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Sequence Analysis, DNA
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Swine
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Swine Diseases / transmission
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Swine Diseases / virology*
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Texas
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Young Adult
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Zoonoses
Substances
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Hepatitis Antibodies
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RNA, Viral