Forty-one patients were treated with Mohs micrographic surgery for well-differentiated superficial squamous cell carcinoma of the lip; 34 had closure of their surgical site by a mucosal advancement flap, and five were allowed to heal by second intention. Cases were limited to T1N0M0 or T2N0M0, these being early superficial lesions. Primary closure by mucosal advancement provides cosmetic and functional healing for these lesions. The combination of Mohs micrographic excision and mucosal advancement closure may be considered standard office or outpatient surgical management of these common tumors.