Direct arylation of unactivated aromatic C-H bonds catalyzed by a stable organic radical

Guo-Ping Yong; Wen-Long She; Yi-Man Zhang; Ying-Zhou Li

doi:10.1039/c1cc14420k

Direct arylation of unactivated aromatic C-H bonds catalyzed by a stable organic radical

Chem Commun (Camb). 2011 Nov 14;47(42):11766-8. doi: 10.1039/c1cc14420k. Epub 2011 Sep 28.

Authors

Guo-Ping Yong¹, Wen-Long She, Yi-Man Zhang, Ying-Zhou Li

Affiliation

¹ Department of Chemistry, University of Science and Technology of China, Hefei 230026, China. [email protected]

PMID: 21952713
DOI: 10.1039/c1cc14420k

Abstract

A stable zwitterionic radical can catalyze direct arylation of unactivated aromatic C-H bonds via a chain homolytic aromatic substitution mechanism in the presence of potassium tert-butoxide.