Accumulating microparticles and direct-writing micropatterns using a continuous-wave laser-induced vapor bubble

Lab Chip. 2011 Nov 21;11(22):3816-20. doi: 10.1039/c1lc20478e. Epub 2011 Sep 28.

Abstract

Through the enhanced photothermal effect, which was achieved using a silver film, a low power weakly focused continuous-wave laser (532 nm) was applied to create a vapor bubble. A convective flow was formed around the bubble. Microparticles dispersed in water were carried by the convective flow to the vapor bubble and accumulated on the silver film. By moving the laser spot, we easily manipulated the location of the bubble, allowing us to direct-write micropatterns on the silver film with accumulated particles. The reported simple controllable accumulation method can be applied to bimolecular detection, medical diagnosis, and other related biochip techniques.