Neurogenic detrusor overactivity in patients with spinal cord injury: evaluation and management

Curr Urol Rep. 2011 Dec;12(6):404-12. doi: 10.1007/s11934-011-0221-1.

Abstract

Lower urinary tract dysfunction can have a significant impact on patients with spinal cord injury. Over the years, many treatment options have become available. This article reviews the assessment and management of neurogenic detrusor overactivity, with a particular focus on articles from the recent literature. Recent guidelines on the subject will be discussed. Management options include antimuscarinics and bladder emptying measures, botulinum toxin A, and neuromodulation in refractory cases and surgery for intractable cases. Recent and relevant publications in these areas will be summarized and discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Disease Management*
  • Global Health
  • Humans
  • Incidence
  • Neuromuscular Agents / therapeutic use*
  • Neurotransmitter Agents / therapeutic use
  • Prognosis
  • Spinal Cord Injuries* / complications
  • Spinal Cord Injuries* / diagnosis
  • Spinal Cord Injuries* / epidemiology
  • Urinary Bladder, Neurogenic* / etiology
  • Urinary Bladder, Neurogenic* / physiopathology
  • Urinary Bladder, Neurogenic* / therapy
  • Urination / physiology*
  • Urologic Surgical Procedures / methods*

Substances

  • Neuromuscular Agents
  • Neurotransmitter Agents