Staphylococcus lugdunensis: the coagulase-negative staphylococcus you don't want to ignore

Expert Rev Anti Infect Ther. 2011 Oct;9(10):901-7. doi: 10.1586/eri.11.110.

Abstract

Staphylococcus lugdunensis is a virulent coagulase-negative staphylococcus (CoNS) that behaves like Staphylococcus aureus. Toxic shock syndrome, osteomyelitis, septic arthritis and postoperative endopthalmitis have been observed. Endocarditis complicated by heart failure, periannular abscess formation and embolic phenomenon have brought particular attention to this CoNS. Mortality rates for endocarditis appear higher when compared with other CoNS. Owing to the laboratory methods used, identification may be misleading. β-lactam antimicrobials are recommended pending sensitivities. Evaluation for endocarditis should be pursued in bacteremic patients due to its pathogenic potential.

Publication types

  • Review

MeSH terms

  • Abscess / drug therapy
  • Abscess / epidemiology
  • Abscess / etiology
  • Abscess / microbiology
  • Abscess / pathology*
  • Anti-Bacterial Agents / administration & dosage*
  • Anti-Bacterial Agents / therapeutic use
  • Arthritis, Infectious / drug therapy
  • Arthritis, Infectious / epidemiology
  • Arthritis, Infectious / etiology
  • Arthritis, Infectious / microbiology
  • Arthritis, Infectious / pathology*
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Bacterial Typing Techniques
  • Coagulase / deficiency
  • Coagulase / genetics
  • Disease Management
  • Endocarditis, Bacterial / drug therapy
  • Endocarditis, Bacterial / epidemiology
  • Endocarditis, Bacterial / etiology
  • Endocarditis, Bacterial / microbiology
  • Endocarditis, Bacterial / pathology*
  • Humans
  • Microbial Sensitivity Tests
  • Osteomyelitis / drug therapy
  • Osteomyelitis / epidemiology
  • Osteomyelitis / etiology
  • Osteomyelitis / microbiology
  • Osteomyelitis / pathology*
  • Shock, Septic / drug therapy
  • Shock, Septic / epidemiology
  • Shock, Septic / etiology
  • Shock, Septic / microbiology
  • Shock, Septic / pathology*
  • Staphylococcal Infections / complications
  • Staphylococcal Infections / diagnosis
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / epidemiology
  • Staphylococcal Infections / microbiology
  • Staphylococcal Infections / pathology*
  • Staphylococcus lugdunensis
  • Treatment Outcome
  • United States

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Coagulase